TUM
Klinikum rechts der Isar Technische Universität München
Neuro-Kopf-Zentrum
Abteilung für Neuroradiologie


Forschungsgruppen und Projekte

 

Neuroimaging and Stimulation


 

Summary

Our mission is to identify and characterize pathologies of both the central and peripheral human nervous system by computed tomography (CT) and advanced magnetic resonance imaging (MRI), particularly diffusion-weighted and functional imaging. We focus on translational approaches, with the aim to be able to directly connect pathology-related changes observed by cutting-edge imaging with therapeutic approaches in the clinical setting. The application of advanced MRI to guide and facilitate non-invasive neurostimulation during multi-modal approaches (e.g. combination of MRI with transcranial stimulation techniques) complements our efforts.

Projects

  • Development of cutting-edge MRI and fiber tractography for imaging of the central and peripheral nervous system.
  • Application of multi-sequence MRI to detect and characterize consequences of traumatic brain injury and concussion.
  • Implementation of novel MRI protocols to shorten acquisition times and improve image quality.
  • Timely resolved MRI of the cerebrovascular system and its perfusion.

Grant Support

  • German Academic Exchange Service (DAAD)
  • German Research Foundation (DFG)
  • Bavarian Research Alliance (BayFOR)
  • Dr.-Ing. Leonhard Lorenz Foundation
  • Joachim Herz Foundation
  • Rolf W. Günther Foundation
  • B. Braun Foundation
  • German Society of Musculoskeletal Radiology (DGMSR)
  • Commission for Clinical Research (KKF, TUM)

Twitter

@NSollmann

Lead

Team

PD Dr. med. Karolin J. Paprottka;
Dr. med. Isabelle Riederer;
Vivian Schultz;
Moritz Roman Hernandez Petzsche;
Magaly Gutbrod-Fernandez ;
Miriam Reichert;
Karina Kupfer

Partners

  • Prof. Dr. J. S. Kirschke, PD Dr. T. Baum, PD Dr. C. Maegerlein, PD Dr. B. J. Schwaiger, Dr. M. Probst (Neuroradiology, TUM)
  • Dr. H. Liebl, Dr. M. Dieckmeyer, Dr. Dr. E. Burian, Dr. M. T. Berndt, Dr. T. Finck, Dr. J. Göttler, Dr. M. T. Löffler (Neuroradiology, TUM)
  • PD Dr. C. Preibisch, S. Kaczmarz, L. Schmitzer (Neuro MR Munich, TUM)
  • Prof. Dr. D. C. Karampinos, D. Weidlich, C. Böhm (Body Magnetic Resonance Research, TUM)
  • PD Dr. Dr. V. Riedl, G. Castrillon (Neuroenergetics of the Human Brain, TUM)
  • Prof. Dr. S. M. Krieg, PD Dr. S. Ille, Dr. C. Negwer (Neurosurgery, TUM)
  • Prof. Dr. J. Hermsdörfer (Human Movement Science, TUM)
  • Prof. Dr. M. Beer (Radiology, Ulm University)
  • Prof. Dr. F. Wolf, Fabian Czappa (Computer Science, Technical University of Darmstadt)
  • Dr. T. Greve (Neurosurgery, LMU)
  • Prof. Dr. I. K. Koerte (cBrain, LMU & Harvard Medical School, Boston, USA)
  • Prof. Dr. P. B. Noel, K. Mei (Perelman School of Medicine, UPenn, Philadelphia, USA)
  • Prof. Dr. R. Krug (University of California, San Francisco, USA)
  • Prof. Dr. P. Julkunen (University of Eastern Finland, Kuopio, Finland)
  • Andrey Zhylka (Eindhoven University of Technology, Eindhoven, Netherlands)


 

Selected Publications

Sollmann N, Tanigawa N, Ringel F, Zimmer C, Meyer B, Krieg SM. Language and its right-hemispheric distribution in healthy brains: an investigation by repetitive transcranial magnetic stimulation. Neuroimage. 2014 Nov 15;102 Pt 2:776-88.

Sollmann N*, Negwer C*, Tussis L, Hauck T, Ille S, Maurer S, Giglhuber K, Bauer JS, Ringel F, Meyer B, Krieg SM. Interhemispheric connectivity revealed by diffusion tensor imaging fiber tracking derived from navigated transcranial magnetic stimulation maps as a sign of language function at risk in brain tumor patients. J Neurosurg. 2017 Jan;126(1):222-233.

Sollmann N, Tanigawa N, Bulubas L, Sabih J, Zimmer C, Ringel F, Meyer B, Krieg SM. Clinical Factors Underlying the Inter-individual Variability of the Resting Motor Threshold in Navigated Transcranial Magnetic Stimulation Motor Mapping. Brain Topogr. 2017 Jan;30(1):98-121.

Sollmann N*, Echlin PS*, Schultz V, Viher PV, Lyall AE, Tripodis Y, Kaufmann D, Hartl E, Kinzel P, Forwell LA, Johnson AM, Skopelja EN, Lepage C, Bouix S, Pasternak O, Lin AP, Shenton ME*, Koerte IK*. Sex differences in white matter alterations following repetitive subconcussive head impacts in collegiate ice hockey players. Neuroimage Clin. 2017 Nov 21;17:642-649.

Sollmann N*, Weidlich D*, Cervantes B, Klupp E, Ganter C, Kooijman H, Rummeny EJ, Zimmer C, Kirschke JS, Karampinos DC. High Isotropic Resolution T2 Mapping of the Lumbosacral Plexus with T2-Prepared 3D Turbo Spin Echo. Clin Neuroradiol. 2019 Jun;29(2):223-230.

Sollmann N, Weidlich D, Klupp E, Cervantes B, Ganter C, Zimmer C, Rummeny EJ, Baum T, Kirschke JS, Karampinos DC. T2 mapping of the distal sciatic nerve in healthy subjects and patients suffering from lumbar disc herniation with nerve compression. MAGMA. 2020 Oct;33(5):713-724.

Castrillon G, Sollmann N, Kurcyus K, Razi A, Krieg SM, Riedl V. The physiological effects of noninvasive brain stimulation fundamentally differ across the human cortex. Sci Adv. 2020 Jan 31;6(5):eaay2739. eCollection 2020 Jan.

Sollmann N*, Zhang H*, Fratini A, Wildschuetz N, Ille S, Schröder A, Zimmer C, Meyer B, Krieg SM. Risk Assessment by Presurgical Tractography Using Navigated TMS Maps in Patients with Highly Motor- or Language-Eloquent Brain Tumors. Cancers (Basel). 2020 May 17;12(5):E1264.

Finck T, Gempt J, Krieg SM, Meyer B, Zimmer C, Wiestler B, Kirschke JS, Sollmann N. Assessment of the Extent of Resection in Surgery of High-Grade Glioma-Evaluation of Black Blood Sequences for Intraoperative Magnetic Resonance Imaging at 3 Tesla. Cancers (Basel). 2020 Jun 15;12(6):E1580.

Sollmann N*, Zhang H*, Kelm A, Schröder A, Meyer B, Pitkänen M, Julkunen P, Krieg SM. Paired-pulse navigated TMS is more effective than single-pulse navigated TMS for mapping upper extremity muscles in brain tumor patients. Clin Neurophysiol. 2020 Dec;131(12):2887-2898.


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